In this series we look at the ingredients in our Perfect Liver Detox Support supplement. If you are new to detox programs, you can start with our article on the Dangers of Toxins.

Milk Thistle (Silybum marianum),

Milk thistle has been used medicinally as a “liver remedy” for almost 2,000 years. Today scientists know that the active ingredient in milk thistle, silymarin and its 3 subparts, are responsible for its liver protecting abilities.

Studies show that milk thistle regenerates injured liver cells in cases of liver toxicity. It protects the liver from toxins by not only preventing toxins from entering the liver cells but also by removing toxins from these cells. Milk thistle increases glutathione, a potent antioxidant responsible for much of the detoxification processes in the liver.

Milk Thistle Health Benefits:

  • Stimulates phase 2 liver detoxification pathways
  • Protects the liver from toxin overload
  • Enhances liver function
  • Contains powerful antioxidants
  • Supports the liver secondary to alcohol abuse or hepatitis
  • Reduces risk of gallstones
  • Promotes healthy skin
  • Promotes healthy cholesterol levels
  • Promotes healthy blood sugar levels and body mass index in type 2 diabetics

Not all Milk Thistle is created equal:

The Milk Thistle in Perfect Liver Detox Support is of the highest quality and has been extensively tested for contaminants and potency. It contains 80% silymarin yielding all 6 of its isomers by HPLC : silibinin A, silibinin B, isosilibinin A, isosilibinin B, silidianin, and silicristin. Silibinin is the most active of these subparts, and is largely responsible for the benefits attributed to silymarin. 75% of the silymarin content of the milk thistle in this product is silibinin (A and B).

How Much Milk Thistle Is in Perfect Liver Detox Support?

Perfect Liver Detox Support contains 150mg of Milk Thistle Extract per serving, which yields 120mg of Silymarin. It is recommended to take 2-3 servings per day (300-450mg of Milk Thistle and 240-360mg of Silymarin in a daily dose).

Why We Include This Dosage of Milk Thistle (Silymarin)

The bioflavonoid group in milk thistle, Silymarin, has been identified and targeted as the active component of the Milk Thistle herb. These bioflavonoids stimulate and protect the liver at a dose of 70-200 mg three times a day. One serving of Silymarin in Perfect Liver Detox Support is 120 mg.

References:

World J Hepatol. 2014 Mar 27;6(3):144-9. doi: 10.4254/wjh.v6.i3.144.
Nat Prod Commun. 2013 Dec;8(12):1801-10.
Curr Drug Targets. 2013 Dec;14(14):1659-66.
Adv Exp Med Biol. 2012;771:381-95.
World J Gastroenterol. 2011 May 14;17(18):2288-301. doi: 10.3748/wjg.v17.i18.2288
Hussain SA. Silymarin as an adjunct to glibenclamide therapy improves long-term and postprandial glycemic control and body mass index in type 2 diabetes. J Med Food 2007;10:543-7.
Velussi M, Cernogoi AM, De Monte A, et al. Long-term (12 months) treatment with an antioxidant drug (silymarin) is effective on hyperinsulinemia, exogenous insulin need and malondialdehyde levels in cirrhotic diabetic patients. J Hepatology 1997;26:871-9.
J Agric Food Chem. 2008 Jun 11;56(11):3966-72. doi: 10.1021/jf703694u. Epub 2008 May 14.


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